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Unconventional initiation of PINK1/Parkin mitophagy by Optineurin

There were no differences in the incidence of treatment-related adverse events between the groups

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We anticipate that if any non-opioid treatments for pain relief qualify during CY 2026, any potential CMS review process would be similar to the other existing quarterly approval processes, such as OPPS New Technology APC process or the CMS HCPCS application process, where CMS evaluates and approves products on a more frequent basis than annual rulemaking